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Global • 2026-10-31, 01:04 GMT • ~1 min read

Japanese scientists find protein that may explain age-related fertility decline

جاپانی سائنس دانوں نے پروٹین دریافت کر لیا جو عمر کے ساتھ زرخیزی میں کمی کی وضاحت کر سکتا ہے

जापानी वैज्ञानिकों को प्रोटीन मिला जो उम्र के साथ प्रजनन क्षमता में कमी की वजह समझा सकता है

Japanese scientists find protein that may explain age-related fertility decline

Key points

اہم نکات

मुख्य बातें

  • Researchers in Japan have identified a protein, named OMC1, that helps hold chromosomes together inside egg cells over long periods.
  • The team from Chiba University, Kumamoto University and the Riken institute says the finding, published in the journal Nature Aging, could help explain why fertility falls with age and why older people who ovulate face higher risks of infertility, miscarriage and chromosomal conditions such as Down syndrome.
  • The work so far is based mainly on experiments in mice, and the researchers caution that more study is needed to confirm the protein plays the same role in human eggs and whether it could lead to future fertility treatments.
  • جاپان کے محققین نے او ایم سی ون نامی ایک پروٹین دریافت کیا ہے جو انڈے کے خلیوں کے اندر کروموسومز کو طویل عرصے تک جوڑے رکھنے میں مدد دیتا ہے۔ چیبا یونیورسٹی، کوماموٹو یونیورسٹی اور ریکن انسٹی ٹیوٹ کی ٹیم کا کہنا ہے کہ نیچر ایجنگ جریدے میں شائع ہونے والی یہ دریافت اس بات کی وضاحت کر سکتی ہے کہ عمر کے ساتھ زرخیزی کیوں کم ہوتی ہے اور زیادہ عمر میں حاملہ ہونے والوں میں بانجھ پن، اسقاط حمل اور ڈاؤن سنڈروم جیسی کروموسوم کی خرابیوں کا خطرہ کیوں بڑھ جاتا ہے۔ اب تک یہ کام زیادہ تر چوہوں پر تجربات پر مبنی ہے، اور محققین کا کہنا ہے کہ یہ تصدیق کرنے کے لیے مزید تحقیق کی ضرورت ہے کہ آیا یہ پروٹین انسانی انڈوں میں بھی یہی کردار ادا کرتا ہے اور کیا اس سے مستقبل میں زرخیزی کے علاج میں مدد مل سکتی ہے۔
  • जापान के शोधकर्ताओं ने ओएमसी1 नामक एक प्रोटीन की पहचान की है जो अंडे की कोशिकाओं के अंदर गुणसूत्रों को लंबे समय तक जोड़े रखने में मदद करता है। चिबा विश्वविद्यालय, कुमामोतो विश्वविद्यालय और रिकेन संस्थान की टीम का कहना है कि नेचर एजिंग पत्रिका में प्रकाशित यह खोज यह समझा सकती है कि उम्र के साथ प्रजनन क्षमता क्यों घटती है और अधिक उम्र में गर्भधारण करने वालों में बांझपन, गर्भपात और डाउन सिंड्रोम जैसी गुणसूत्र संबंधी समस्याओं का ख़तरा क्यों बढ़ जाता है। अब तक यह काम मुख्य रूप से चूहों पर प्रयोगों पर आधारित है, और शोधकर्ताओं का कहना है कि यह पुष्टि करने के लिए और अध्ययन की ज़रूरत है कि क्या यह प्रोटीन मानव अंडों में भी यही भूमिका निभाता है और क्या इससे भविष्य में प्रजनन उपचार में मदद मिल सकती है।

Researchers in Japan have identified a protein, named OMC1, that helps hold chromosomes together inside egg cells over long periods. The team from Chiba University, Kumamoto University and the Riken institute says the finding, published in the journal Nature Aging, could help explain why fertility falls with age and why older people who ovulate face higher risks of infertility, miscarriage and chromosomal conditions such as Down syndrome. The work so far is based mainly on experiments in mice, and the researchers caution that more study is needed to confirm the protein plays the same role in human eggs and whether it could lead to future fertility treatments.

جاپان کے محققین نے او ایم سی ون نامی ایک پروٹین دریافت کیا ہے جو انڈے کے خلیوں کے اندر کروموسومز کو طویل عرصے تک جوڑے رکھنے میں مدد دیتا ہے۔ چیبا یونیورسٹی، کوماموٹو یونیورسٹی اور ریکن انسٹی ٹیوٹ کی ٹیم کا کہنا ہے کہ نیچر ایجنگ جریدے میں شائع ہونے والی یہ دریافت اس بات کی وضاحت کر سکتی ہے کہ عمر کے ساتھ زرخیزی کیوں کم ہوتی ہے اور زیادہ عمر میں حاملہ ہونے والوں میں بانجھ پن، اسقاط حمل اور ڈاؤن سنڈروم جیسی کروموسوم کی خرابیوں کا خطرہ کیوں بڑھ جاتا ہے۔ اب تک یہ کام زیادہ تر چوہوں پر تجربات پر مبنی ہے، اور محققین کا کہنا ہے کہ یہ تصدیق کرنے کے لیے مزید تحقیق کی ضرورت ہے کہ آیا یہ پروٹین انسانی انڈوں میں بھی یہی کردار ادا کرتا ہے اور کیا اس سے مستقبل میں زرخیزی کے علاج میں مدد مل سکتی ہے۔

जापान के शोधकर्ताओं ने ओएमसी1 नामक एक प्रोटीन की पहचान की है जो अंडे की कोशिकाओं के अंदर गुणसूत्रों को लंबे समय तक जोड़े रखने में मदद करता है। चिबा विश्वविद्यालय, कुमामोतो विश्वविद्यालय और रिकेन संस्थान की टीम का कहना है कि नेचर एजिंग पत्रिका में प्रकाशित यह खोज यह समझा सकती है कि उम्र के साथ प्रजनन क्षमता क्यों घटती है और अधिक उम्र में गर्भधारण करने वालों में बांझपन, गर्भपात और डाउन सिंड्रोम जैसी गुणसूत्र संबंधी समस्याओं का ख़तरा क्यों बढ़ जाता है। अब तक यह काम मुख्य रूप से चूहों पर प्रयोगों पर आधारित है, और शोधकर्ताओं का कहना है कि यह पुष्टि करने के लिए और अध्ययन की ज़रूरत है कि क्या यह प्रोटीन मानव अंडों में भी यही भूमिका निभाता है और क्या इससे भविष्य में प्रजनन उपचार में मदद मिल सकती है।

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