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Global • 2026-11-01, 15:51 GMT • ~1 min read

New study tests a gentler way to control sickness during chemotherapy

نئی تحقیق: کیموتھراپی کے دوران متلی پر قابو کا نرم طریقہ آزمایا جا رہا ہے

नया अध्ययन: कीमोथेरेपी के दौरान मतली पर काबू का सौम्य तरीका आज़माया जा रहा है

New study tests a gentler way to control sickness during chemotherapy

Key points

اہم نکات

मुख्य बातें

  • A new study is testing whether sickness and vomiting during chemotherapy can be controlled without corticosteroids, drugs that are widely used but can cause side effects and may weaken the body's immune response.
  • In a large trial, patients given other anti-sickness medicines, including netupitant-palonosetron and olanzapine, had similar overall protection from vomiting whether they received a full steroid dose, a single smaller dose, or none at all.
  • Nausea control was slightly worse in the first days without steroids, but steroid side effects were fewer.
  • ایک نئی تحقیق میں یہ آزمایا جا رہا ہے کہ کیا کیموتھراپی کے دوران متلی اور قے پر کورٹیکوسٹیرائیڈز کے بغیر قابو پایا جا سکتا ہے۔ یہ دوائیں عام استعمال ہوتی ہیں لیکن ان کے مضر اثرات ہو سکتے ہیں اور یہ جسم کے مدافعتی نظام کو کمزور کر سکتی ہیں۔ ایک بڑی آزمائش میں جن مریضوں کو متلی روکنے والی دوسری دوائیں دی گئیں، ان میں قے سے بچاؤ تقریباً ایک جیسا رہا، چاہے انہیں سٹیرائیڈ کی پوری خوراک ملی ہو، ایک چھوٹی خوراک یا کوئی سٹیرائیڈ نہ ملا ہو۔ بغیر سٹیرائیڈ کے پہلے دنوں میں متلی کا کنٹرول تھوڑا کمزور رہا، لیکن سٹیرائیڈ کے مضر اثرات کم تھے۔ محققین کا کہنا ہے کہ اس سے کینسر کے مریضوں کے لیے نرم علاج ممکن ہو سکتا ہے۔
  • एक नए अध्ययन में यह आज़माया जा रहा है कि क्या कीमोथेरेपी के दौरान मतली और उल्टी पर कॉर्टिकोस्टेरॉइड के बिना काबू पाया जा सकता है। ये दवाएं आम तौर पर इस्तेमाल होती हैं लेकिन इनके दुष्प्रभाव हो सकते हैं और ये शरीर की रोग प्रतिरोधक क्षमता को कमज़ोर कर सकती हैं। एक बड़े परीक्षण में जिन मरीज़ों को मतली रोकने वाली दूसरी दवाएं दी गईं, उनमें उल्टी से बचाव लगभग एक जैसा रहा, चाहे उन्हें स्टेरॉयड की पूरी खुराक मिली हो, एक छोटी खुराक या कोई स्टेरॉयड न मिला हो। बिना स्टेरॉयड के पहले दिनों में मतली का नियंत्रण थोड़ा कमज़ोर रहा, लेकिन स्टेरॉयड के दुष्प्रभाव कम थे। शोधकर्ताओं का कहना है कि इससे कैंसर के मरीज़ों के लिए सौम्य इलाज संभव हो सकता है।

A new study is testing whether sickness and vomiting during chemotherapy can be controlled without corticosteroids, drugs that are widely used but can cause side effects and may weaken the body's immune response. In a large trial, patients given other anti-sickness medicines, including netupitant-palonosetron and olanzapine, had similar overall protection from vomiting whether they received a full steroid dose, a single smaller dose, or none at all. Nausea control was slightly worse in the first days without steroids, but steroid side effects were fewer. Researchers say the findings could lead to gentler treatment for cancer patients.

ایک نئی تحقیق میں یہ آزمایا جا رہا ہے کہ کیا کیموتھراپی کے دوران متلی اور قے پر کورٹیکوسٹیرائیڈز کے بغیر قابو پایا جا سکتا ہے۔ یہ دوائیں عام استعمال ہوتی ہیں لیکن ان کے مضر اثرات ہو سکتے ہیں اور یہ جسم کے مدافعتی نظام کو کمزور کر سکتی ہیں۔ ایک بڑی آزمائش میں جن مریضوں کو متلی روکنے والی دوسری دوائیں دی گئیں، ان میں قے سے بچاؤ تقریباً ایک جیسا رہا، چاہے انہیں سٹیرائیڈ کی پوری خوراک ملی ہو، ایک چھوٹی خوراک یا کوئی سٹیرائیڈ نہ ملا ہو۔ بغیر سٹیرائیڈ کے پہلے دنوں میں متلی کا کنٹرول تھوڑا کمزور رہا، لیکن سٹیرائیڈ کے مضر اثرات کم تھے۔ محققین کا کہنا ہے کہ اس سے کینسر کے مریضوں کے لیے نرم علاج ممکن ہو سکتا ہے۔

एक नए अध्ययन में यह आज़माया जा रहा है कि क्या कीमोथेरेपी के दौरान मतली और उल्टी पर कॉर्टिकोस्टेरॉइड के बिना काबू पाया जा सकता है। ये दवाएं आम तौर पर इस्तेमाल होती हैं लेकिन इनके दुष्प्रभाव हो सकते हैं और ये शरीर की रोग प्रतिरोधक क्षमता को कमज़ोर कर सकती हैं। एक बड़े परीक्षण में जिन मरीज़ों को मतली रोकने वाली दूसरी दवाएं दी गईं, उनमें उल्टी से बचाव लगभग एक जैसा रहा, चाहे उन्हें स्टेरॉयड की पूरी खुराक मिली हो, एक छोटी खुराक या कोई स्टेरॉयड न मिला हो। बिना स्टेरॉयड के पहले दिनों में मतली का नियंत्रण थोड़ा कमज़ोर रहा, लेकिन स्टेरॉयड के दुष्प्रभाव कम थे। शोधकर्ताओं का कहना है कि इससे कैंसर के मरीज़ों के लिए सौम्य इलाज संभव हो सकता है।

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